Liam Eaton

Ph.D. Student (2018- )

Publications: 

Kadamani KL, Rehnamaie-Tajadod R, Eaton L, Bengstson J, Ojaghi M, Cheng H and Pamenter ME (2024). What can naked mole-rats teach us about ameliorating hypoxia-related human diseases? Annals of the New York Academy of Sciences.

Eaton L, Bengtsson J, Welch I, Halal AK and Pamenter ME (2024). Sources of reactive oxygen species in normoxic and hypoxic naked mole-rat brain. Medical Research Archives.

Eaton L, Welch I, Halal AK, Bengtsson J and Pamenter ME (2023). Apocynin reduces dihydroethidium fluorescence in naked mole-rat cortex independently of NADPH oxidase. Comparative Biochemistry and Physiology A.

Eaton L, Wang T, Roy M, and Pamenter ME (2023). Naked mole-rat cortex maintains reactive oxygen species homeostasis during in vitro hypoxia or ischemia and reperfusion. Current Neuropharmacology.

Eaton L and Pamenter ME (2022). Is NADPH critical to maintain redox homeostasis in hypoxia-tolerant naked mole-rat brain? Reactive Oxygen Species.

Hadj-Moussa H, Eaton L, Cheng H, Pamenter ME and Storey KB (2022). Naked mole-rats resist the accumulation of hypoxia-induced oxidative damage. Comparative Biochemistry and Physiology A.

Eaton L and Pamenter ME (2022). What to do with low O2: redox adaptations in vertebrates native to hypoxic environments. Comparative Biochemistry and Physiology A.

D’Alessio S, Cheng H, Eaton L, Kraev I, Pamenter ME and Lange S (2022). Acute hypoxia alters extracellular vesicle signatures and the brain citrusllinome of naked mole-rats (Heterocephalus glaber). International Journal of Molecular Sciences.

Ingelson-Filpula WA, Cheng H, Eaton L, Pamenter ME and Storey KB (2022). Small RNA sequencing in hypoxic naked mole-rat hearts suggests microRNA regulation of RNA- and translation-related processes. FEBS Letters.

Hadj-Moussa H, Chiasson S, Cheng H, Eaton L, Storey KB and Pamenter ME (2021). MicroRNA-mediated inhibition of AMPK coordinates tissue-specific downregulation of skeletal muscle metabolism in hypoxic naked mole-rats. Journal of Experimental Biology.

Wang TH, Eaton L, and Pamenter ME (2020). Nitric oxide homeostasis is maintained during acute in vitro hypoxia and following reoxygenation in naked mole-rat but not mouse cortical neurons. Comparative Biochemistry and Physiology A.

Karen Kadamani

Honours B.Sc. Student (2019-2020); Ph.D. Student (2020- )

Publications:

Kadamani KL, Logan SM and Pamenter ME (2024). Does hypoxia constrain innate pathogen defence? Acta Physiologica.

Kadamani KL, Rehnamaie-Tajadod R, Eaton L, Bengstson J, Ojaghi M, Cheng H and Pamenter ME (2024). What can naked mole-rats teach us about ameliorating hypoxia-related human diseases? Annals of the New York Academy of Sciences.

Ingelson-Filpula WA, Kadamani KL, Ojaghi M, Pamenter ME and Storey KB (2024). Hypoxia-induced down regulation of RNA m6A protein machinery in the naked mole-rat heart. Biochimie.

Gloria Lamontagne

Honours B.Sc. Student (2023- )

Amar Bhandari

USRO undergraduate student (2023- )

Deanna Turchyn

Undergraduate student (2024- )

Neha Erukulla

Honours B.Sc. student (2024- )

Areeb Shaifuddien

Undergraduate student (2024- )

Lisa Borecky

M.Sc. Student (2015-2018)

M.Sc. Thesis title: Hypoxia inducible factor and the control of hypoxic ventilatory and metabolic responses in Mus Musculus and heterocephalus glaber.

Publications:

Dzal, Seow, Borecky, Chung, Gill, Milsom and Pamenter (2019). Glutamatergic receptors modulate normoxic but not hypoxic ventilation and metabolism in naked mole rats. Frontiers in Physiology

Borecky LG and Pamenter ME (2017). Oxygen sensing and transcriptional regulation of adaptive hypoxic responses. In: Chemosensory sensors and systems: evolutionary significance biological effects, and new insights. New York, USA: Nova Science (M. Brandt, ed.).

Alexia Kirby

B.Sc. Student (2015-2016); M.Sc. Student (2016-2018)

B.Sc. Thesis title: Behavioural, thermal, and metabolic strategies of the naked mole rat, Hetercephalus glaber, in hypoxia.

M.Sc. Thesis title: Metabolic adaptations to acute hypoxia in naked mole rats.

Publications:

Hart DW, Bennett NC, Best C, van Jaarsveld B, Cheng H, Ivy CM, Kirby AM, Munro D, Sprenger RJ, Storey KB, Milsom WK and Pamenter ME (2023). The relationship between hypoxia exposure and circulating cortisol levels in social and solitary African mole-rats. General and Comparative Endocrinology.

Cheng H, Sebaa R, Malholtra N, Lacoste B, El Hankouri Z, Kirby A, Bennett NC, van Jaarseld B, Hart DW, Tattersall GJ, Harper ME and Pamenter ME (2021). Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1. Nature Communications.

Ivy CM, Sprenger RJ, Bennett NC, van Jaarsveld B, Hart D, Kirby AM, Yaghoubi D, Storey KB, Milsom WK and Pamenter (2020). The hypoxia-tolerance of eight related African mole-rat species rivals that of naked mole-rats despite divergent ventilatory and metabolic strategies in severe hypoxia. Acta Physiologica.

Vandewint A, Zhu-Palowsky A, Kirby A, Tattersall GJ and Pamenter ME. (2019). Evaporative cooling and vasodilation mediate thermoregulation in naked mole rats during normoxia but not hypoxia. Journal of Thermal Biology.

Houlahan, Kirby, Dzal, Fairman, and Pamenter (2018). Divergent behavioural responses to acute hypoxia between individuals and groups of naked mole rats. Comparative Physiology and Biochemistry

Kirby, Fairman, and Pamenter (2018). Atypical behavioural, metabolic, and thermoregulatory responses to hypoxia in the naked mole rat (Hetercephalus glaber). Journal of Zoology

Ilacqua, Kirby, and Pamenter (2017). Behavioural responses of naked mole rats to acute hypoxia and anoxia. Biology Letters

Max Clayson

Honours B.Sc. Student (2016-2017)

B.Sc. Thesis title: The role of carbonic anhydrase in modulating metabolic and ventilatory responses to hypercapnia in naked mole-rats

Publication: 

Clayson M, Devereaux MEM, and Pamenter ME (2020). Neurokinin-1 receptor activation is sufficient to restore the hypercapnic ventilatory response in the Substance P-deficient naked mole-rat. American Journal of Physiology.

Chelsea Houlahan

Honours B.Sc. Student (2016-2017)

B.Sc. Thesis title: The effects of hypoxia on the behavioural and thermoregulatory huddling responses of the naked mole rat

Publication:

Houlahan, Kirby, Dzal, Fairman, and Pamenter (2018). Divergent behavioural responses to acute hypoxia between individuals and groups of naked mole rats. Comparative Physiology and Biochemistry

Sulaf Elkhalifa

Honours B.Sc. Student (2016-2017)

B.Sc. Thesis title: Behavioural and thermal responses to hypercapnia in naked mole-rats

Publication:

Branigan, Elkhalifa, and Pamenter. (2018). Behavioral responses to environmental hypercapnia in two eusocial species of African mole rats. Journal of Comparative Physiology A

Aaron Ilacqua

Honours B.Sc. Student (2015-2016)

B.Sc. Thesis title: Behavioural and thermal responses of individual naked mole rats to environmental hypoxia within their thermoneutral zone

Publication:

Ilacqua, Kirby, and Pamenter (2017). Behavioural responses of naked mole rats to acute hypoxia and anoxia. Biology Letters

Garrett Fairman

NSERC USRA awardee (summer 2016)

Publications:

Houlahan, Kirby, Dzal, Fairman, and Pamenter (2018). Divergent behavioural responses to acute hypoxia between individuals and groups of naked mole rats. Comparative Physiology and Biochemistry

Kirby, Fairman, and Pamenter (2018). Atypical behavioural, metabolic, and thermoregulatory responses to hypoxia in the naked mole rat (Hetercephalus glaber). Journal of Zoology

Sharn Gill

B.Sc. Student Volunteer (2015-2016)

Project title: Exploring the role of glutamatergic receptors in the control of ventilatory responses to acute and chronic hypoxia in naked mole rats

Publication:

Dzal, Seow, Borecky, Chung, Gill, Milsom and Pamenter (2019). Glutamatergic receptors modulate normoxic but not hypoxic ventilation and metabolism in naked mole rats. Frontiers in Physiology.